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Richard J. Miron et al.: 20 years of Enamel Matrix Derivative – the past, the present and the future (a systematic review)

  This systematic review on EMD aims to: 1) provide the biological background necessary to understand the rational for the use of EMD (commercial name: Straumann® Emdogain®) for periodontal regeneration, 2) present animal and human histological evidence of periodontal regeneration following EMD application, 3) provide clinically relevant indications for the use of EMD and 4) discuss future avenues of research including key early findings leading to the development of Osteogain, a new carrier system for EMD specifically developed with better protein adsorption to bone grafting materials. The review is dedicated to Professor Lars Hammarström, to honour his landmark and pioneering work in discovering the regenerative capacities of enamel matrix proteins. Richard J. Miron, Anton Sculean, David L. Cochran, Stuart Froum, Giovanni Zucchelli, Carlos Nemcovsky, Nikos Donos, Staale Petter Lyngstadaas, James Deschner, Michel Dard, Andreas Stavropoulos, Yufeng Zhang, Leonardo Trombelli, Adrian Kasaj, Yoshinori Shirakata, Pierpaolo Cortellini, Maurizio Tonetti, Giulio Rasperini, Søren Jepsen, Dieter D. Bosshardt: Twenty years of enamel matrix derivative: the past, the present and the future. Journal of Clinical Periodontology: Volume 43, Issue 8, August 2016, pages 668–683. A great contribution to our understanding of how biologics can act as mediators for periodontal regeneration On June 5th, 2015 at Europerio 8, a group of leading experts were gathered to discuss what has now been 20 years of documented evidence supporting the clinical use of enamel matrix derivative (EMD). Original experiments led by Lars Hammarström demonstrated that enamel matrix proteins could serve as key regenerative proteins capable of promoting periodontal regeneration including new cementum, with functionally oriented inserting new periodontal ligament fibers, and new alveolar bone formation. This pioneering work and vision by Lars Hammarström has paved the way to an enormous amount of publications related to its biological basis and clinical use. 20 years later it is clear that all these studies have greatly contributed to our understanding of how biologics can act as mediators for periodontal regeneration and have provided additional clinical means to support tissue regeneration of the periodontium. “EMD has remained one of the gold standards for periodontal regeneration using biologics and it remains of interest to discover how the next 20 years of intensive research will further improve EMD clinical outcomes.” Dr. Richard Miron Looking forward to the next 20 years of research Dr. Miron’s final remarks: “It remains hard to believe that over 20 years have now passed since enamel matrix derivative was first introduced as a regenerative agent for periodontal tissues. Equally as surprising, it remains one of the only biomaterials still available for clinical use capable of histologically demonstrating true periodontal regeneration with new cementum formation, periodontal ligament and alveolar bone along with inserting Sharpeys fibers spanning the periodontal apparatus. It is clear that over the years, we have learned a great deal regarding the biological roles of specific enamel matrix proteins and future investigation is constantly underway to further characterize their effects on cell and tissue behavior. It also becomes clinically important to further investigate the use of EMD in both carrier systems described to determine if regenerative outcomes can be even further improved by slight modifications in EMD-carrier systems or through minimally invasive surgeries. During these 20 years over 900 publications have documented the use of EMD for a variety of in vitro and in vivo studies as well as numerous clinical trials. EMD has remained one of the gold standards for periodontal regeneration using biologics and it remains of interest to discover how the next 20 years of intensive research will further improve EMD clinical outcomes.” Dr. Richard Miron BMSC, MSc, PhD, DDS Nova Southeastern University, Florida Dr. Richard Miron is an Adjunct Faculty in the Department of Periodontology, Nova Southeastern University, Fort Lauderdale, Florida, USA. He completed his undergraduate degree in Medical Science and a Masters in Cell Biology at the University of Western Ontario in Canada, a PhD in Molecular and Cell Biology at the University of Bern, Switzerland and a Doctor of Dental Surgery degree at the University of Laval, Canada. In 2015, while serving as the Head of the Cell Biology Laboratory at the University of Bern, he concurrently completed his dr. med. dent degree. He has previously performed numerous short stay post-doctoral research fellowships at the University of Wuhan in China in 2011, 2012 and 2014 and has since co-supervised numerous Master and PhD candidates as an external visiting scholar. He has authored and co-authored over 90 peer-reviewed scientific publications mostly connected to his main research interests including enamel matrix proteins for bone and periodontal regeneration, bioactive growth factors, osteoinductive bone grafting materials and guided bone regeneration in implant dentistry. He has recently been awarded many internationally recognized top young investigators awards including the Andre Schroeder Research Prize from the International Team for Implantology (ITI) (2016), The Robert Frank Award (2015), the International Association of Dental Research (IADR) Young investigator of the Year in the field of Implant Dentistry (2015), the Canadian IADR Hatton Award recipient (2015), and the American Academy of Implant Dentistry Young Investigator Grant Award (2014). Subscribe here and get the full version of Dr. Miron’s review [* are mandatory fields] First Name* Last Name* Email* Confirm Email Country* Please selectAfghanistanAlbaniaAlgeriaAmerican SamoaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBoliviaBosnia and HerzegovinaBotswanaBrazilBruneiBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaColombiaComorosCongoCosta RicaCroatiaCubaCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEast TimorEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFijiFinlandFranceFrench GuianaFrench PolynesiaGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuamGuatemalaGuineaGuinea-BissauGuyanaHaitiHondurasHong KongHungaryIcelandIndiaIndonesiaIranIraqIrelandIsraelItalyJamaicaJapanJordanKazakhstanKenyaKiribatiNorth KoreaSouth KoreaKuwaitKyrgyzstanLaosLatviaLebanonLesothoLiberiaLibyaLiechtensteinLithuaniaLuxembourgMacedoniaMadagascarMalawiMalaysiaMaldivesMaliMaltaMarshall IslandsMauritaniaMauritiusMexicoMicronesiaMoldovaMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew ZealandNicaraguaNigerNigeriaNorwayNorthern Mariana IslandsOmanPakistanPalauPalestinePanamaPapua New GuineaParaguayPeruPhilippinesPolandPortugalPuerto RicoQatarRomaniaRussiaRwandaSaint Kitts and NevisSaint LuciaSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbia and MontenegroSeychellesSierra LeoneSingaporeSlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSpainSri LankaSudanSurinameSwazilandSwedenSwitzerlandSyriaTaiwanTajikistanTanzaniaThailandTogoTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVatican CityVenezuelaVietnamVirgin Islands, BritishVirgin Islands, U.S.YemenZambiaZimbabwe Consent* I confirm to be a dental professional who is eligible to receive clinical and medical content. By accessing, using or subscribing to starget.straumann.com, I acknowledge that I have read, understood and agreed to the Terms of Use. If you do not agree to the Terms of Use, you may not access, use or subscribe to starget.straumann.com.   Submit The post Richard J. Miron et al.: 20 years of Enamel Matrix Derivative – the past, the present and the future (a systematic review) appeared first on STARGET COM.

Straumann® CARES® Visual 10: Enjoying the freedom of choice

  Straumann® CARES® Visual 10 has been recently released to enhance your daily practice experience. The new software upgrade brings the user interface to the next level and enables to design a wider range of prosthetic restorations, followed by direct transfer into the milling solution of your choice; either in-lab or at a central milling center. It ensures access to state-of-the-art design options, generates open STL files and enables the design of complex, highly precise and esthetic restorations – all within a validated and streamlined Straumann digital workflow. Straumann® CARES® Visual is user-friendly and provides high-end results allowing you to choose between centralized, or in-lab manufacture. Every Straumann® scanner is supplied with the fully integrated CARES® Visual software to enable the design of a wide range of prosthetic restorations followed by direct transfer into the milling solution of your choice; either in-lab, or at a central milling center. Straumann® CARES® Visual 10 Crowns with milling: the CARES® user is now able to create crowns that are partially covered by a functional milling surface. NOTE: An object can be merged and unmerged individually in the CAD module. The finalizing step is no longer needed. Changes to finished designs can be made instantly. Straumann® CARES® Visual 10 Crowns with milling: the CARES® user is now able to create crowns that are partially covered by a functional milling surface. NOTE: An object can be merged and unmerged individually in the CAD module. The finalizing step is no longer needed. Changes to finished designs can be made instantly. Straumann® CARES® Visual 10 Combining partial frameworks with CAD: the CARES® user is able to combine partial frameworks with a designed object in the CAD module. This allows the design of combined removable restorations in one step. Straumann® CARES® Visual 10 Combining partial frameworks with CAD: the CARES® user is able to combine partial frameworks with a designed object in the CAD module. This allows the design of combined removable restorations in one step. Straumann® CARES® Visual 10 Combining partial frameworks with CAD: the CARES® user is able to combine partial frameworks with a designed object in the CAD module. This allows the design of combined removable restorations in one step. Straumann® CARES® Visual 10 Virtual and Real Waxing Workflow (only for Straumann in-lab milling and third party milling workflow): By using the new virtual waxing order the user can create a bridge for tooth-borne and implant-borne restorations that are based on a scanned bridge, as a waxing reference or as a fully digitally designed denture. Note: for best results with the real waxing function, we recommend using the CARES® 3 Series or CARES® 7 Series scanners. Straumann® CARES® Visual 10 Virtual and Real Waxing Workflow (only for Straumann in-lab milling and third party milling workflow): By using the new virtual waxing order the user can create a bridge for tooth-borne and implant-borne restorations that are based on a scanned bridge, as a waxing reference or as a fully digitally designed denture. Note: for best results with the real waxing function, we recommend using the CARES® 3 Series or CARES® 7 Series scanners. Straumann® CARES® Visual 10 Virtual and Real Waxing Workflow (only for Straumann in-lab milling and third party milling workflow): By using the new virtual waxing order the user can create a bridge for tooth-borne and implant-borne restorations that are based on a scanned bridge, as a waxing reference or as a fully digitally designed denture. Note: for best results with the real waxing function, we recommend using the CARES® 3 Series or CARES® 7 Series scanners. Straumann® CARES® Visual 10 Virtual and Real Waxing Workflow (only for Straumann in-lab milling and third party milling workflow): By using the new virtual waxing order the user can create a bridge for tooth-borne and implant-borne restorations that are based on a scanned bridge, as a waxing reference or as a fully digitally designed denture. Note: for best results with the real waxing function, we recommend using the CARES® 3 Series or CARES® 7 Series scanners. OUR OFFERING FOR DENTAL LABS FOR DENTISTS FOR DENTAL LABS The Straumann® CARES® offering for dental labs connects carefully selected, best-in-class dental equipment (scanners, CARES® Visual software, milling machines, high-temperature furnaces) with the latest digital technology and premium materials to provide a seamless, fully validated workflow for the state-of-the-art dental lab. You can be sure that our solution will 1. enable you to offer a broader range of prosthetic solutions and services, 2. increase your lab’s productivity and efficiency and 3. let you enjoy the benefits of future-proof hardware and software! FOR DENTISTS Replace traditional dental impressions with highly accurate digital data! Based on our novel 3D capture technique called Multi-scan Imaging™, the extremely compact Straumann® CARES® Intraoral Scanner allows dentists and clinicians to quickly and easily create digital impressions. The remarkably small handpiece, one of the smallest on the market today, is particularly patient-friendly. Based on the open STL data format, digital impressions can be sent directly to your lab partner via Straumann® CARES® Connect. THE BROCHURES OUR “DIGITAL PERFORMANCE” ROADSHOW 2016/17 STAY TUNED! The post Straumann® CARES® Visual 10: Enjoying the freedom of choice appeared first on STARGET COM.

Straumann® CARES®: seamless communication from scan to manufacture with Straumann® scanners and CARES® Visual software

  In Straumann® 3Series and 7Series scanners, high scanning accuracy is ensured by utilizing the latest generation Blue Laser Illumination system with proven high precision mechanical and optical components. CAPTURE CLINICAL DATA IN HIGH PRECISION SCANS STRAUMANN® 3SERIES Unattended scanning and design of up to 12 copings in 10 minutes Produce high quality scans within a 90 mm × 90 mm × 90 mm chamber . STRAUMANN® 7SERIES Unattended scanning and design of up to 30 copings in 15 minutes Scan fully articulated models in the large volume scanning chamber (140 mm × 140 mm × 140 mm) DIGITAL DESIGN AND TRANSFER Every Straumann® scanner, is supplied with the fully integrated CARES® Visual software to enable the design of a wide range of prosthetic restorations followed by direct transfer into the milling solution of your choice; either in-lab, or at a central milling center. Eliminate complexity and the need to migrate between different systems Open to importing/exporting STL files Dedicated CAD software enables the design of complex, highly precise and esthetic restorations Proven and established scanning and CAD processes Straumann software support OUR OFFERING FOR DENTAL LABS FOR DENTISTS FOR DENTAL LABS The Straumann® CARES® offering for dental labs connects carefully selected, best-in-class dental equipment (scanners, CARES® Visual software, milling machines, high-temperature furnaces) with the latest digital technology and premium materials to provide a seamless, fully validated workflow for the state-of-the-art dental lab. You can be sure that our solution will 1. enable you to offer a broader range of prosthetic solutions and services, 2. increase your lab’s productivity and efficiency and 3. let you enjoy the benefits of future-proof hardware and software! FOR DENTISTS Replace traditional dental impressions with highly accurate digital data! Based on our novel 3D capture technique called Multi-scan Imaging™, the extremely compact Straumann® CARES® Intraoral Scanner allows dentists and clinicians to quickly and easily create digital impressions. The remarkably small handpiece, one of the smallest on the market today, is particularly patient-friendly. Based on the open STL data format, digital impressions can be sent directly to your lab partner via Straumann® CARES® Connect. THE BROCHURES OUR “DIGITAL PERFORMANCE” ROADSHOW 2016/17 STAY TUNED! The post Straumann® CARES®: seamless communication from scan to manufacture with Straumann® scanners and CARES® Visual software appeared first on STARGET COM.

e-book: Online Marketing for Dental Practices (Straumann® Patient Pro)

  In a world that is changing at a fast pace, not all dental practices have the resources, time, or knowledge to deal with the topics of Online Marketing. With Straumann Straumann® Patient Pro, Straumann offers dedicated patient marketing and practice building services to its customers. If you are interested in an introduction to this topic, sign up for our newsletter and get the e-book “Online Marketing for Dental Practices” for free! Almost 50% of patients seeking a dental implant treatment go online at some point in their decision making process. It is essential that you can grab their attention during their patient journey. Unfortunately, the online world is ever evolving and it is hard to keep up; especially if your core competence is treating patients and you have very limited time to invest into marketing. But don’t worry – the elementary steps in this e-book will help you following the right path! (Note: certain products and services mentioned in this article may not be available or not yet available in all countries. Please contact your local Straumann subsidiary or distributor for information on availability.) First Name* Last Name* Email* Confirm Email Country* Please selectAfghanistanAlbaniaAlgeriaAmerican SamoaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBoliviaBosnia and HerzegovinaBotswanaBrazilBruneiBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaColombiaComorosCongoCosta RicaCroatiaCubaCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEast TimorEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFijiFinlandFranceFrench GuianaFrench PolynesiaGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuamGuatemalaGuineaGuinea-BissauGuyanaHaitiHondurasHong KongHungaryIcelandIndiaIndonesiaIranIraqIrelandIsraelItalyJamaicaJapanJordanKazakhstanKenyaKiribatiNorth KoreaSouth KoreaKuwaitKyrgyzstanLaosLatviaLebanonLesothoLiberiaLibyaLiechtensteinLithuaniaLuxembourgMacedoniaMadagascarMalawiMalaysiaMaldivesMaliMaltaMarshall IslandsMauritaniaMauritiusMexicoMicronesiaMoldovaMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew ZealandNicaraguaNigerNigeriaNorwayNorthern Mariana IslandsOmanPakistanPalauPalestinePanamaPapua New GuineaParaguayPeruPhilippinesPolandPortugalPuerto RicoQatarRomaniaRussiaRwandaSaint Kitts and NevisSaint LuciaSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbia and MontenegroSeychellesSierra LeoneSingaporeSlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSpainSri LankaSudanSurinameSwazilandSwedenSwitzerlandSyriaTaiwanTajikistanTanzaniaThailandTogoTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVatican CityVenezuelaVietnamVirgin Islands, BritishVirgin Islands, U.S.YemenZambiaZimbabwe Consent* I confirm to be a dental professional who is eligible to receive clinical and medical content. By accessing, using or subscribing to starget.straumann.com, I acknowledge that I have read, understood and agreed to the Terms of Use. If you do not agree to the Terms of Use, you may not access, use or subscribe to starget.straumann.com.   Submit 1References a. Ipsos Mori (2011), Psychographics of Patients (US, DE), Straumann proprietary data b. Institute Riegl (2011), Survey Patient Satisfaction (CH, DE, FR, IT, ES) The post e-book: Online Marketing for Dental Practices (Straumann® Patient Pro) appeared first on STARGET COM.

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