#Education 17. Apr 2026

Two-piece Zirconia compared to titanium implants: clinical and radiological outcomes

A selected scientific recommendation by Dr. Marcin Maj: "One -Year Analysis of Clinical and Radiological Outcomes of Two - Piece Zirconia Compared to Titanium Implants: A Multicenter Prospective Randomized Clinical Trial" by Marc Balmer, Michael Payer, Anke Steinwender, Valentin Herber, Ronald E. Jung, Sebastian Kühl.

STUDY OBJECTIVES AND METHODS

The purpose of this study was to evaluate the clinical performance of two -piece zirconia implants with screw -retained abutments compared to titanium implants after 1 year of loading. In this multicenter, prospective, randomized clinical trial, 61 two -piece zirconia and 61 titanium implant s were placed and restored with single crowns. Evaluations were performed at implant placement, crown delivery, and 1 - year post -loading. Peri -implant Marginal Bone Loss (MBL), survival rate, early wound healing index, and s oft tissue parameters were assessed. Intergroup comparisons of continuous outcomes were performed using Linear Mixed -Effects Models accounting for center and potential confounders. Categorical variables were analyzed using the chi -square or Fisher's exact test. Survival was analyzed using Kaplan -Meier estimates. Significance was set at p < 0.05.


RESULTS

  • No significant differences were found between the two implant types.
  • Mean MBL from implantation to crown insertion was 1.10 ± 0.78 mm for titanium and 0.94 ± 0.67 mm for zirconia implants.
  • No significant additional bone loss occurred over the subsequent year, with changes of 0.07 ± 0.55 mm and 0.08 ± 0.51 mm for titanium and zirconia, respectively.
  • After 1 year, zirconia implants showed a 100% survival rate, while titanium implants showed 96.5% with two failures.
  • At 1 year, differences in probing depths, plaque accumulation, and Papilla Bleeding Index were not statistically significant.

CONCLUSIONS

After 1 year of loading, no statistically significant differences in MBL, implant survival, or peri -implant health were found between zirconia and titanium implants, indicating no clinical superiority. Zirconia implants may therefore be considered a viable alternative in single -tooth implant restorations. Adapted from M Balmer et al., Clin Oral Implants Res. 2026 Jan 22 , for more info about this publication, click  HERE.

This review is part of the Straumann "Scientific Highlights Newsletter 1/26".


More studies:

  • One-Year Analysis of Clinical and Radiological Outcomes of Two-Piece Zirconia Compared to Titanium Implants: A Multicenter Prospective Randomized Clinical Trial
  • Osteogenic Differentiation on Nonthermal Atmospheric Plasma-Treated versus SLActive® Titanium and Titanium-Zirconium Implants: An In Vitro Comparative Study
  • The Effect of Age and Use of Enamel Matrix Derivative on Implant Loss
  • Impact of Zirconia and Titanium Implant Surfaces of Different Roughness on Oral Epithelial Cells
  • Impact of Two Implant-Abutment Connection Types on Crestal Bone Stability: A 3-Year Comparative Split-Mouth Clinical Trial
  • Full-Arch Implant Rehabilitation Integrating Mandibular Movement Records Using Complete Digital Workflows: A Case Report
  • Clinical evaluation and bone loss prediction of titanium-zirconium implants: A retrospective study of 1-5-year follow-up
  • Scientific evaluation of design and surface advances in Straumann implants