Biologics

Straumann® Emdogain®: Bringing biology to oral surgery.

Straumann® Emdogain® is a mix of enamel matrix proteins that, when applied to a clean tooth root surface or oral wound, form an extracellular matrix that stimulates cells and processes that are fundamental for periodontal regeneration1 and soft tissue wound healing2. Numerous scientific studies provide clinical evidence of the application of Straumann® Emdogain® in different indications: periodontal regeneration, gingival recession, and oral wound healing. As the first dental implant company to do so, Straumann incorporates a biologic in the surgical procedure of implant placement as a standard step in order to improve wound healing. 

  • Regeneration

    By modulating the wound healing process, Emdogain® induces the regeneration of a functional attachment in regenerative periodontal procedures3 and accelerates the soft tissue wound healing process following oral surgical procedures such as implantations.4

  • Peace of Mind

    Emdogain® is backed by extensive and long-term clinical documentation. Over the past 20 years it has been used in over 2 million patients and is documented in over 1,000 scientific publications, including 600 clinical publications.6

  • Handling

    As it is a gel, Emdogain® is easy to apply, even when the defect is difficult to access.

  • Comfort

    Emdogain® leads to better tooth prognosis and esthetic results. Less post-surgical discomfort5 such as pain or swelling is reported after a procedure with Emdogain® compared to the same procedure without Emdogain®.

  • Predictability

    Emdogain® leads to significantly improved clinical parameters in intraosseous defects7 and root coverage procedures9, including in the long term10, compared to the same surgical procedures without the addition of Emdogain®.

How can we help you?

Emdogain® for wound healing

Orchestrating oral wound healing.

Surgical interventions such as implant placements or periodontal procedures always involve the risk of undesired events, ranging from pain and swelling of oral soft tissues to wound healing complications. As Straumann® Emdogain® accelerates soft tissue healing2 *, it promotes the success of your implantations and other oral procedures by reducing the risk of wound complications, improving both patient comfort, and improving the esthetic result.

*compared to a treatment without Emdogain®

How can we help you?

Emdogain® for periodontal regeneration

Orchestrating periodontal regeneration.

Straumann® Emdogain® is designed to be used as an adjunct to surgical periodontal procedures. As demonstrated by human histological studies3, it promotes the predictable regeneration of cementum, periodontal ligament, and alveolar bone lost due to periodontal disease or trauma, thereby significantly improving the clinical outcome of your periodontal treatment (compared with an open flap debridement procedure alone)7 as shown by long-term clinical studies.8

How can we help you?

Emdogain® for gingival recession

Reverse gum recession naturally.

Root coverage is becoming an increasingly frequent treatment request, mostly due to growing esthetic demands of patients. Adding Straumann® Emdogain® to your root coverage surgical procedure means improved esthetic results thanks to more root coverage9 * – including in the long term10 – and more keratinized tissue formation9. Using Straumann® Emdogain® during your root coverage procedure instead of a connective tissue graft (CTG) may lead to comparable long-term clinical results10 as well as improved patient comfort. 

*compared to a treatment without Emdogain®

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Downloads

Documents

Orchestrating periodontal regeneration and oral wound healing.

Straumann® Emdogain®
490.133/en/B/00 01/17 31.01.2017 PDF, 1 MB Download

Orchestrating wound healing.

Straumann® Emdogain®
490.124/en/A/00 02/16 28.02.2016 PDF, 1 MB Download

Periodontal Treatment Guide

Straumann® Emdogain®
490.273/en/A/00 12/17 01.02.2018 PDF, 4 MB Download

Straumann® Emdogain®

Frequently Asked Questions
490.368/en/A/00 12/17 01.02.2018 PDF, 106 KB Download

Straumann® Emdogain®

Biomaterials@Straumann®. Because one option is not enough.
490.280/en/A/00 12/17 01.02.2018 PDF, 334 KB Download

Straumann® Emdogain® and botiss mucoderm®

Prof. Giovanni Zucchelli’s technique for the treatment of gingival recession
702154/en/A/00 02/17 28.02.2017 PDF, 590 KB Download

Straumann® Emdogain® for the treatment of intrabony defects

The Single Flap Approach
490.117/en/A/00 09/15 30.09.2015 PDF, 995 KB Download

Surgical procedures with Straumann® Emdogain® to support oral wound healing

Basic Information
490.123/en/A/00 12/15 31.12.2015 PDF, 389 KB Download

When one option is not enough.

Biomaterials@Straumann®
490.118/en/E/00 09/17 23.11.2017 PDF, 4 MB Download
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Videos & Animations

Straumann® Emdogain®

Orchestrating wound healing.
V0065-en 01.06.2017 MP4, 20 MB

Straumann® Emdogain®. Mode of action.

V0115-en 01.02.2018 M4V, 250 MB

Treatment of Class I gingival recession with Straumann® Emdogain® and mucoderm®

Prof. Giovanni Zucchelli
V0116-en 01.02.2018 M4V, 367 MB

Using Emdogain® to improve oral wound healing

Voices of Emdogain® users
V1024-en 01.02.2018 M4V, 332 MB

Wellbeing and faster recovery after oral surgery

Information for patient
V0125-en 01.02.2018 MP4, 70 MB
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Scientific evidence

Straumann® Emdogain® in oral wound healing

Scientific and clinical evidence (2017)
490.367/en/A/00 12/17 01.02.2018 PDF, 272 KB Download

Straumann® Emdogain® in periodontology

Clinical evidence (2017)
490.366/en/A/00 12/17 01.02.2018 PDF, 313 KB Download

Catalogs

Product Catalog 2018/2019

Straumann International Edition
452.200/en/C/00 07/18 08.08.2018 PDF, 13 MB Download
See all resources...

References

1 Bosshardt DD. Biological mediators and periodontal regeneration: a review of enamel matrix proteins at the cellular and molecular levels. J Clin Periodontol. 2008 Sep;35(8 Suppl):87-105. 2 Miron RJ, Dard M, Weinreb M. Enamel matrix derivative, inflammation and soft tissue wound healing. J Periodontal Res. 2015 Oct;50(5):555-69. 3 Sculean A, Chiantella GC, Windisch P, Donos N. Clinical and histologic evaluation of human intrabony defects treated with an enamel matrix protein derivative (Emdogain). Int J Periodontics Restorative Dent. 2000 Aug;20(4):374-81. 4 Guimarães GF, de Araújo VC, Nery JC, Peruzzo DC, Soares AB. Microvessel Density Evaluation of the Effect of Enamel Matrix Derivative on Soft Tissue After Implant Placement: A Preliminary Study. Int J Periodontics Restorative Dent. 2015 Sep-Oct;35(5):733-8. 5 Jepsen S, Heinz B, Jepsen K, Arjomand M, Hoffmann T, Richter S, Reich E, Sculean A, Gonzales JR, Bödeker RH, Meyle J. A randomized clinical trial comparing enamel matrix derivative and membrane treatment of buccal Class II furcation involvement in mandibular molars. Part I: Study design and results for primary outcomes. J Periodontol. 2004 Aug;75(8):1150-60. 6 according to PUBMED search for “Emdogain” OR “enamel matrix derivative” Tonetti MS, Lang NP, Cortellini P, Suvan JE, Adriaens P, Dubravec D, Fonzar A, Fourmousis I, Mayfield L, Rossi R, Silvestri M, Tiedemann C, Topoll H, Vangsted T, Wallkamm B. Enamel matrix proteins in the regenerative therapy of deep intrabony defects. J Clin Periodontol. 2002 Apr;29(4):317-25. 8 Sculean A, Kiss A, Miliauskaite A, Schwarz F, Arweiler NB, Hannig M. Ten-year results following treatment of intra-bony defects with enamel matrix proteins and guided tissue regeneration. J Clin Periodontol. 2008 Sep;35(9):817-24. 9 Pilloni A, Paolantonio M, Camargo PM. Root coverage with a coronally positioned flap used in combination with enamel matrix derivative: 18-month clinical evaluation. J Periodontol. 2006 Dec;77(12):2031-9. 10 McGuire MK, Scheyer ET, Nunn M. Evaluation of human recession defects treated with coronally advanced flaps and either enamel matrix derivative or connective tissue: comparison of clinical parameters at 10 years. J Periodontol. 2012 Nov;83(11):1353-62.