Roxolid® SLActive®

Biocompatibilidade avançada.

Investigação recente mostra que a superfície SLActive® estimula uma reação celular anti-inflamatória precoce, comparativamente com a superfície sem SLActive, conforme medição in vitro, expressa como uma redução nos marcadores pró-inflamatórios* e um aumento nos marcadores anti-inflamatórios**.31​

A SLActive® está associada a uma reação acrescida dos macrófagos anti-inflamatórios na fase precoce da cicatrização, tanto nos animais saudáveis como nos diabéticos. Este pode ser um mecanismo importante para melhorar a cicatrização óssea sob condições sistémicas comprometidas.21 

*Il1b, Il6, Tnfa, IL-1beta, IL-6, TNF-alfa, (pró-inflamatórios)​
**Il10, Tgfb1, Chil3, Rentla, IL-4, IL-10 (anti-inflamatórios)

Novos dados acerca da reação celular anti-inflamatória da SLActive® foram apresentados na 95ª Assembleia Geral da Associação Internacional de Investigação Dentária, EUA.

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Acordo de utilização de dados*

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Referências

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