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The study assessed the influence of transgingival healing compared with submerged healing on the peri-implant bone maintenance around a novel, fully tapered implant (Straumann® BLX, Roxolid® SLActive®) in a healed crestal ridge in minipigs. It was seen that the loaded and unloaded implants displayed comparable levels of osseointegration and equivalent marginal bone levels. This qualifies the implant placement protocol with respect to the osteotomy dimensions and subcrestal placement protocol for immediate loading.