Straumann® Emdogain®
Mastering periodontal regeneration and oral wound healing.

Straumann® Emdogain® is a unique gel containing enamel matrix derivative. This mixture of natural proteins can induce biological processes that usually take place during the development of the periodontium and may stimulate certain cells involved in the healing process of soft and hard tissues.

Features and benefits

Emdogain® induces true regeneration

By modulating the wound healing process, Emdogain® induces the regeneration of a functional attachment in periodontal procedures (as evidenced by human histological data⁵,⁶)


Emdogain® improves wound healing in oral surgical procedures

By promoting angiogenesis modulating the production of factors related to inflammation⁹ and thanks to its anti-microbial effect toward oral pathogens Emdogain® accelerates the wound healing process of oral surgical procedures


Emdogain® increased the predictability of your periodontal procedures

Emdogain® leads to:

  • significantly improved clinical parameters in intra-osseous defects compared to open flap debridement procedures alone12
  • increased root coverage achieved when used in a coronally advanced flap (CAF) compared to CAF alone13, and leads to results comparable to CAF + Connective Tissue Graft14

Emdogain® helps you achieve patient satisfaction

  • When used to treat intra-osseous defects, Emdogain® contributes to improve your patients’ dental prognosis
  • When used in oral surgical procedures in general, Emdogain® accelerates wound closure15, and reduces post surgical pain and swelling16
  • When used in periodontal plastic procedures around teeth and implants, Emdogain® may improve the esthetics of the results thanks to improved wound healing

Emdogain® is easy to apply

Because Emdogain® is a gel, it is easy to apply, even in defects difficult to access


Emdogain® means peace of mind

Emdogain® is backed by extensive and long term clinical documentation. It is documented in over 1000 scientific publications including 600 clinical publications17 and 10 year data14,18


Straumann® Emdogain® on youTooth

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Straumann® Biomaterials
Product portfolio

Learn more about our Biomaterials portfolio.

All Straumann® Emdogain® Solutions

Downloads

Documents

Implant Health Quick Guide Straumann® Emdogain® and Straumann® Emdogain® FL

Mastering peri-implant treatment.
490.646/en/A/00 07/20 14.08.2020 PDF, 276 KB Download

Prof. Giovanni Zucchelli’s technique for the treatment of gingival recession

Straumann® Emdogain® and Straumann® Soft Tissue Graft - low-res
702172/en/A/00 06/17 11.09.2019 PDF, 853 KB Download

Straumann Emdogain / Straumann Emdogain FL

25 years. Mastering periodontal regeneration, oral wound healing and peri-implant treatment.
490.651/en/A/00 11/20 21.12.2020 PDF, 4 MB Download

Straumann® Biomaterials Master any challenge.

Product portfolio - low-res
490.561-490.579/en/A/00 12/19 20.02.2020 PDF, 9 MB Download

Straumann® Emdogain®

Frequently Asked Questions - low-res
490.368/en/A/00 12/17 01.02.2018 PDF, 106 KB Download

Straumann® Emdogain® / Straumann® Emdogain® FL

Clinical evidence
490.366/en/B/00 10/20 27.10.2020 PDF, 1 MB Download

Straumann® Emdogain® and botiss mucoderm®

Prof. Giovanni Zucchelli’s technique for the treatment of gingival recession - low-res
702154/en/A/00 02/17 28.02.2017 PDF, 590 KB Download

Straumann® Emdogain® for the treatment of intrabony defects

The Single Flap Approach
490.117/en/A/00 09/15 702068 30.09.2015 PDF, 995 KB Download

Straumann® Emdogain®. Wellbeing and faster recovery after oral surgery.

Patient Information
490.365/en/A/00 08/17 01.02.2018 PDF, 299 KB Download

Surgical procedures with Straumann® Emdogain® to support oral wound healing

Basic Information - low-res
490.123/en/A/00 12/15 702069 31.12.2015 PDF, 389 KB Download
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Videos & Animations

Case 1. Single flap approach in combination with Straumann® Emdogain®

Prof. Leonardo Trombelli
V0121-en 13.03.2018 M4V, 605 MB

Case 2. Single flap approach in combination with Straumann® Emdogain®

Prof. Leonardo Trombelli
V0122-en 22.03.2018 M4V, 556 MB

Emdogain Song

V0168-en 19.12.2018 MP4, 414 MB

Straumann® Emdogain®

Orchestrating wound healing.
V0065-en 01.06.2017 MP4, 20 MB

Straumann® Emdogain®. Mode of action.

V0115-en 01.02.2018 M4V, 250 MB

Symposium Bern 2019: Interview Anton Sculean

Straumann LIVE
V0325 25.03.2021 MP4, 284 MB

Treatment of Class I gingival recession with Straumann® Emdogain® and mucoderm®

Prof. Giovanni Zucchelli
V0116-en 01.02.2018 M4V, 367 MB

Using Emdogain® to improve oral wound healing

Voices of Emdogain® users
V1024-en 01.02.2018 M4V, 332 MB

Wellbeing and faster recovery after oral surgery

Information for patient
V0125-en 01.02.2018 MP4, 70 MB
See all resources...

Catalogs

Product Catalog 2021 - INTERNATIONAL EDITION

Straumann® BLX Implant System - interactive
450.012/en/D/00 01/21 PDF, 3 MB Download

Product Catalog 2021 - INTERNATIONAL EDITION

Straumann® BLX Implant System - low-res
450.012/en/D/00 01/21 PDF, 2 MB Download

Product Catalog 2021/2022 - SPECIAL EDITION

Straumann® Product Catalog - interactive
452.201/en/E/00 03/21 24.03.2021 PDF, 13 MB Download

Product Catalog 2021/2022 - INTERNATIONAL EDITION

Straumann® Product Catalog - interactive
452.200/en/E/00 03/21 15.11.2019 PDF, 12 MB Download

Product Catalog 2021/2022 - SPECIAL EDITION

Straumann® Product Catalog - low-res
452.201/en/E/00 03/21 01.07.2019 PDF, 8 MB Download

Product Catalog 2021/2022 - INTERNATIONAL EDITION

Straumann® Product Catalog - low-res
452.200/en/E/00 03/21 28.06.2019 PDF, 8 MB Download
See all resources...

References

5 McGuire MK, et al. A Prospective, Cased-Controlled Study Evaluating the use of Enamel Matrix Derivative on Human Buccal Recession Defects: A Human Histologic Examination. J Periodontol. 2016 Feb 1:1-34.
6 Sculean A, et al. Clinical and histologic evaluation of
human intrabony defects treated with an enamel matrix protein derivative (Emdogain). Int J Periodontics Restorative Dent. 2000;20:374–381.
7 Aspriello SD, et al. Effects of enamel matrix derivative on vascular endothelial growth factor expression and microvessel density in
gingival tissues of periodontal pocket: a comparative study. J Periodontol. 2011 Apr;82(4):606-12.
8 Guimarães et al. Microvessel Density
Evaluation of the Effect of Enamel Matrix Derivative on Soft Tissue After Implant Placement: A Preliminary Study. Int J Periodontics Restorative
Dent. 2015 Sep-Oct;35(5):733-8.
9 Sato et al. Enamel matrix derivative exhibits anti-inflammatory properties in monocytes J Periodontol.
Mar 2008;79(3):535-40
10 Arweiler et al. Antibacterial effect of an enamel matrix protein derivative on in vivo dental biofilm vitality. Clin Oral Investig. 2002 Dec;6(4):205‑9. Epub 2002 Nov 14.
11 Maymon-Gil T, et al. Emdogain Promotes Healing of a Surgical Wound in the Rat Oral Mucosa. J. Periodontol. 2016 Jan 16:1-16.
12 Tonetti et al. Enamel matrix proteins in the regenerative therapy of deep intrabony defects – A multicenter,
randomized, controlled clinical trial. J Clin Periodontology 2002;29;317-325
13 Tonetti MS et al. Clinical efficacy of periodontal plastic surgery
procedures: consensus report of Group 2 of the 10th European Workshop on Periodontology. J Clin Periodontol. 2014 Apr;41 Suppl 15:S36-43
14 McGuire MK, et al. Evaluation of human recession defects treated with coronally advanced flaps and either enamel matrix derivative or
connective tissue: comparison of clinical parameters at 10 years. J Periodontol. 2012 Nov;83(11):1353-62
15 Villa O et al. J Periodontol. A Proline-Rich Peptide Mimic Effects of EMD in Rat Oral Mucosal Incisional Wound Healing. 2015 Dec;86(12):1386-95.
16 Jepsen S, et al. A randomized clinical trial comparing enamel matrix derivative and membrane treatment of buccal Class II furcation involvement in mandibular molars. Part I: Study design and results for primary outcomes.J Periodontol. 2004 Aug;75(8):1150-60.
17 According to PUBMED - search term “Emdogain" or "enamel matrix derivative”.
18 Sculean A, et al. Ten-year results following treatment of intra-bony defects with enamel matrix proteins and guided tissue
regeneration. J Clin Periodontol. 2008 Sep;35(9):817-24