Labrida BioClean™

for effective debridement of teeth and dental implant surfaces.

Labrida BioClean™ is a clinically proven solution for effective debridement of teeth and dental implant surfaces.
Labrida BioClean™ is designed for cleaning of osseointegrated dental implants and/or teeth (pocket depths ≥ 4mm). The fibers of Labrida BioClean™ brush are made out of chitosan, whose bacteriostatic and anti-inflammatory properties are documented.10-12

For efficient implant care1-5
Effective and gentle cleaning of the implant surface*

Maintains peri–implant health1-3, 6-9
Treatment and prevention of peri-implant mucositis and peri-implantitis, supporting peri-implant health

Increases patient comfort compared to Ti curettes2
More comfortable for patient compared to treatment with Ti curettes 

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1 Wohlfahrt JC, Aass AM, Koldsland OC: Treatment of Peri-Implant mucositis using a resorbable chitosan brush- a pilot clinical study EAO 22nd, annual scientific meeting, poster presentation, Dublin 2013
2 Wohlfahrt JC, Aass AM, Koldsland OC: Treatment of peri-implant mucositis with a chitosan brush-A pilot randomized clinical trial. Int J Dent Hyg 2019;17:170-176.
3 Wohlfahrt JC, Evensen BJ, Zeza B, Jansson H, Pilloni A, Roos-Jansaker AM, Di Tanna GL, Aass AM, Klepp M, Koldsland OC: A novel non-surgical method for mild peri-implantitis- a multicenter consecutive case series. Int J Implant Dent 2017;3:38.
4 Larsen OI, Enersen M, Kristoffersen AK, Wennerberg A, Bunæs DF, Lie SA, Leknes KN: Antimicrobial Effects of Three Different Treatment Modalities on Dental Implant Surfaces. J Oral Implantol. 2017 Dec;43(6):429-436. doi: 10.1563/aaid-joi-D-16-00147. Epub 2017 Oct 3.
5 Wohlfahrt et al. 2012. A SEM analysis of titanium implant surfaces after instrumentation with BioClean or titanium curette, unpublished data (included in Technical file)
6 Costa FO, Takenaka-Martinez S, Cota LO, Ferreira SD, Silva GL, Costa JE. Peri-implant disease in subjects with and without preventive maintenance: a 5-year follow-up. J Clin Periodontol. 2012 Feb;39(2):173-81. doi: 10.1111/j.1600-051X.2011.01819.x. Epub 2011 Nov 2
7 Roccuzzo M, Layton DM, Roccuzzo A, Heitz-Mayfield LJ. Clinical outcomes of periimplantitis treatment and supportive care: A systematic review. Clin Oral Implants Res. 2018 Oct;29 Suppl 16:331-350. doi: 10.1111/clr.13287.
8 Monje A, Aranda L, Diaz KT, Alarcón MA, Bagramian RA, Wang HL, Catena A. Impact of Maintenance Therapy for the Prevention of Peri-implant Diseases: A Systematic Review and Meta-analysis. J Dent Res. 2016 Apr;95(4):372-9. doi: 10.1177/0022034515622432. Epub 2015 Dec 23.
9 Jepsen S, Berglundh T, Genco R, Aass AM, Demirel K, Derks J, Figuero E, Giovannoli JL, Goldstein M, Lambert F, Ortiz-Vigon A, Polyzois I, Salvi GE, Schwarz F, Serino G, Tomasi C, Zitzmann NU.Primary prevention of peri-implantitis: managing peri-implant mucositis. J Clin Periodontol. 2015 Apr;42 Suppl 16:S152-7. doi: 10.1111/jcpe.12369.
10 Arancibia R et al. Effects of chitosan particles in periodontal pathogens and gingival fibroblasts. J Dent Res. 2013 Aug;92(8):740-5. doi: 10.1177/0022034513494816. Epub 2013 Jun 20.
11 Suyeon Kim Competitive Biological Activities of Chitosan and Its Derivatives: Antimicrobial, Antioxidant, Anticancer, and Anti-Inflammatory Activities Hindawi International Journal of Polymer Science Volume 2018, Article ID 1708172, 13 pages
12 Saini S, Dhiman A, Nanda S Immunomodulatory Properties of Chitosan: Impact on Wound Healing and Tissue Repair. Endocr Metab Immune Disord Drug Targets. 2020 May 2. doi:10.2174/1871 530320666200503054605. [Epub ahead of print]