Straumann® SLActive®

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fibrinネットワークのSEM画像。Empa, 2016より転載

SLActive® は、高い予測可能性を備え、迅速なオッセオインテグレーションを実現します。1-8
最近の研究では、非常に困難な治療プロトコールや易感染性状態の患者でもSLActive ® インプラントの臨床パフォーマンスが判明しました。9-11

残存率

複数の研究において、5年および10年の追跡調査で95.1〜98.8％の高く安定した生存率が報告されています。12-18
骨の維持

10年後の平均骨吸収量は0.5〜1mmと報告されています。（ベースラインはインプラント荷重時）。13
インプラント歯周炎の罹患率

10年間の追跡調査において、インプラント周囲炎の有病率は1.8％と低い水準であったことが報告されています。13-14

Celebrate 20 Years of

Straumann® SLActive®

Proven by science. Trusted in practice.

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SUPPORTING SCIENTIFIC EVIDENCE

Osteogenic Differentiation on Nonthermal Atmospheric Plasma-Treated versus SLActive® Titanium and Titanium-Zirconium Implants: An In Vitro Comparative Study

S G Kocaayan, G Pulat, Zby Cevik, S Enhos

Niger J Clin Pract 2026 Jan 01;29(1):30-42
詳細を表示（PubMed） 詳細を表示（PubMed）
Buccal Bone Wall Thickness Dictates the Extent of Vertical Buccal Bone Loss Following Implant Placement: A Preclinical Study

Jean-Claude Imber, Andrea Roccuzzo, Alberto Monje, Benjamin Pippenger, Dieter D Bosshardt, Anton Sculean, Daniel Buser

J Clin Periodontol 2025 Dec;52(12):1791-1801
詳細を表示（PubMed） 詳細を表示（PubMed）

PRODUCT CATALOG

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参考文献

1 Straumann SLActive implants compared to Straumann SLA implants. Lang NP, Salvi GE, Huynh-Ba G, Ivanovski S, Donos N, Bosshardt DD.Early osseointegration to hydrophilic and hydrophobic implant surfaces in humans.Clin Oral Implants Res.2011 Apr;22（4）:349-56. doi: 10.1111/j.1600-0501.2011.02172.x.
2 Rupp F, Scheideler L, Olshanska N, de Wild M, Wieland M, Geis-Gerstorfer J. Enhancing surface free energy and hydrophilicity through chemical modification of microstructured titanium implant surfaces. Journal of Biomedical Materials Research A, 76(2):323-334, 2006. 
3 De Wild M. Superhydrophilic SLActive® implants. Straumann document 151.52, 2005; Katharina Maniura.Laboratory for Materials – Biology Interactions Empa, St. Gallen, Switzerland, Protein and blood adsorption on Ti and TiZr implants as a model for osseointegration.EAO 22nd Annual Scientific Meeting, October 17 – 19 2013, Dublin.Kopf BS, Schipanski A, Rottmar M, Berner S, Maniura-Weber K, Enhanced differentiation of human osteoblasts on Ti surfaces pre-treated with human whole blood.Acta Biomaterialia.2015 June; 19: 180-190.Kopf BS, Ruch S, Berner S, Spencer ND, Maniura-Weber K, The role of nanostructures and hydrophilicity in osseointegration: In-vitro protein-adsorption and blood-interaction studies. J Biomed Mater Res A. 2015 August; 103 (8): 2661-2672. 
4 Schwarz, F., et al., Bone regeneration in dehiscence-type defects at non-submerged and submerged chemically modified (SLActive®) and conventional SLA® titanium implants: an immunohistochemical study in dogs. J Clin.Periodontol.35.1 (2008): 64-75.
5 Rausch-fan X, Qu Z, Wieland M, Matejka M, Schedle A. Differentiation and cytokine synthesis of human alveolar osteoblasts compared to osteoblast-like cells (MG63) in response to titanium surfaces.Dental Materials 2008 Jan;24(1):102-10.Epub 2007 Apr 27.
6 Schwarz F, Herten M, Sager M, Wieland M, Dard M, Becker J. Histological and immunohistochemical analysis of initial and early osseous integration at chemically modified and conventional SLA® titanium implants: Preliminary results of a pilot study in dogs.Clinical Oral Implants Research, 11(4): 481-488, 2007.
7 Raghavendra S, Wood MC, Taylor TD.Int. J. Oral Maxillofac.Implants.2005 May–Jun;20(3):425–31.9.
8 Oates TW, Valderrama P, Bischof M, Nedir R, Jones A, Simpson J, Toutenburg H, Cochran DL.Enhanced implant stability with a chemically modified SLA® surface: a randomized pilot study.Int. J. Oral Maxillofac.Implants.2007;22(5):755–760.
9 Nicolau P, Guerra F, Reis R, Krafft T, Benz K , Jackowski J 10-year results from a randomized controlled multicenter study with immediately and early loaded SLActive implants in posterior jaws.Presented at 25th Annual Scientific Meeting of the European Association of Osseointegration – 29 Sep – 1 Oct 2016, Paris.
10 Nelson, K., Stricker, A., Raguse, J.-D. and Nahles, S. (2016), Rehabilitation of irradiated patients with chemically modified and conventional SLA implants: a clinical clarification.J Oral Rehabil, 43: 871–872. doi:10.1111/joor.12434.
11 Patients treated with dental implants after surgery and radio-chemotherapy of oral cancer.Heberer S, Kilic S, Hossamo J, Raguse J-D, Nelson K. Rehabilitation of irradiated patients with modified and conventional sandblasted, acid-etched implants: preliminary results of a split-mouth study.Clin.Oral Impl.Res.22, 2011; 546–551.

12 Fischer K, Stenberg T.: Prospective 10-year cohort study based on a randomized controlled trial (RCT) on implant-supported full-arch maxillary prostheses. Part 1: sandblasted and acid-etched implants and mucosal tissue. Clin Implant Dent Relat Res. 2012 Dec;14(6):808-15.
13 van Velzen FJ, Ofec R, Schulten EA, Ten Bruggenkate CM. 10-year survival rate and the incidence of peri-implant disease of 374 titanium dental implants with an SLA surface: a prospective cohort study in 177 fully and partially edentulous patients. Clin Oral Implants Res. 2015 Oct;26(10):1121-8
14 Cochran DL, Jackson JM, Bernard JP, ten Bruggenkate CM, Buser D, Taylor TD, Weingart D, Schoolfield JD, Jones AA, Oates TW Jr. A 5-year prospective multicenter study of early loaded titanium implants with a sandblasted and acid-etched surface. Int J Oral Maxillofac Implants. 2011 Nov-Dec;26(6):1324-32.
15 Cochran D, Oates T, Morton D, Jones A, Buser D, Peters F. Clinical field trial examining an implant with a sand-blasted, acid-etched surface. J Periodontol. 2007 Jun;78(6):974-82.
16 Bornstein MM, Schmid B, Belser UC, Lussi A, Buser D. Early loading of non-submerged titanium implants with a sandblasted and acid-etched surface. 5-year results of a prospective study in partially edentulous patients. Clin Oral Implants Res. 2005 Dec;16(6):631-8.
17 Roccuzzo M, Aglietta M, Bunino M, Bonino L. Early loading of sandblasted and acid-etched implants: a randomized-controlled double-blind split-mouth study. Five-year results. Clin Oral Implants Res. 2008 Feb;19(2):148-52.
18 Derks J, Schaller D, Håkansson J, Wennström JL, Tomasi C, Berglundh T. Effectiveness of Implant Therapy Analyzed in a Swedish Population: Prevalence of Peri-implantitis. J Dent Res. 2016 Jan;95(1):43-9. doi